5-(4-Chlorophenyl)-3-(phenylsulfonyl)pyridin-2(1H)-one CAS 400089-33-0
| CAS No. | 400089-33-0 |
| Molecular Formula | C17H12ClNO3S |
| Molecular Weight | 345.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-Chlorophenyl)-3-(phenylsulfonyl)pyridin-2(1H)-one (CAS 400089-33-0), molecular formula C17H12ClNO3S and molecular weight 345.80 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(4-Chlorophenyl)-3-(phenylsulfonyl)pyridin-2(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 345.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO3S |
| Molecular Weight | 345.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-phenylacetamide (CAS 332161-36-1)
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- 2-{[4-(4-chlorophenyl)-5-phenyl-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 727717-72-8)
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Recommended Standards
- 4-Ethyl 2-(2-propen-1-yl) 5-[(2-chloroacetyl)amino]-3-methyl-2,4-thiophenedicarboxylate (CAS 730951-35-6)
- Methyl 5-(2-chlorobenzamido)benzo[b]thiophene-2-carboxylate (CAS 477847-55-5)
- 4-[(Benzenesulfonyl)methyl]-6-chloro-2-(pyridin-4-yl)pyrimidine (CAS 337923-87-2)
- Methyl 5-(3-chlorobenzamido)benzo[b]thiophene-2-carboxylate (CAS 477847-51-1)
- 2,5-Dichloro-3,6-difluoroaniline (CAS 1806274-47-4)
- 5-Fluoro-2-hydroxybenzamide (CAS 56874-97-6)
- 7-Chloro-3-methylbenzofuran-2-carboxylic Acid (CAS 32565-18-7)
- N-((3-phenylisoxazol-5-yl)methyl)acetamide (CAS 13608-58-7)
- Bisoprolol Impurity 74 (CAS 14435-48-4)
- tert-Butyl 3-(2,3-difluoro-4-methylphenyl)-3-hydroxyazetidine-1-carboxylate (CAS 1697803-56-7)
- Methyl 3-methylpyrrolidine-3-carboxylate (CAS 1111943-58-8)
- 3,5-Difluoro-4-((3-methylbutan-2-yl)amino)benzonitrile (CAS 1384720-84-6)
- Fluorescent red 610 reactive (CAS 482379-41-9)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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