1-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)ethan-1-one CAS 400878-26-4
| CAS No. | 400878-26-4 |
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)ethan-1-one.
1-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)ethan-1-one (CAS 400878-26-4), molecular formula C15H12ClFO2 and molecular weight 278.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)ethan-1-one (C15H12ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClFO2 |
| Molecular Weight | 278.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-((3-Chloro-4-methoxyphenyl)sulfonyl)propanoic acid (CAS 1017225-49-8)
- 2-((2-Chloro-4-fluorobenzyl)oxy)-5-methylbenzaldehyde (CAS 1281726-96-2)
- 3-Chloro-5-(morpholinosulfonyl)pyridin-4-ol (CAS 1352497-26-7)
- 5-Chloro-4-morpholinopyridine-3-sulfonic acid (CAS 1352507-65-3)
- 2-((2-Chloro-6-fluorobenzyl)oxy)-5-methylbenzaldehyde (CAS 1427023-14-0)
- 2-((2-Chloro-6-fluorobenzyl)oxy)-3-methylbenzaldehyde (CAS 1427026-81-0)
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Recommended Standards
- 1-(2-Chloro-6-fluorobenzyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 338748-74-6)
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- (4-Chlorosulfonylphenyl)carbamic acid octylester (CAS 680185-46-0)
- 2-((tert-Butoxycarbonyl)amino)-4-chlorothiazole-5-carboxylic acid (CAS 612541-07-8)
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- 4-(Chloromethyl)-n-(4-methoxyphenyl)-1,3-thiazol-2-amine hydrochloride (CAS 1049746-46-4)
- 2-Acetyl-6-(trifluoromethyl)isonicotinonitrile (CAS 1393573-81-3)
- 2-Isopropyl-6-nitrophenol (CAS 7545-71-3)
- 8-Bromo-6-methylquinolin-2(1H)-one (CAS 142219-59-8)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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