2,2,2-Trifluoro-N-(pyridin-2-ylmethyl)acetamide CAS 401575-24-4

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2,2,2-Trifluoro-N-(pyridin-2-ylmethyl)acetamide (CAS 401575-24-4) is a high-purity analytical reference standard with the molecular formula C8H7F3N2O and a molecular weight of 204.15 g/mol.

The molecular framework of 2,2,2-Trifluoro-N-(pyridin-2-ylmethyl)acetamide (C8H7F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), 2,2,2-Trifluoro-N-(pyridin-2-ylmethyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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