2-(Pyridin-2-yl)quinazolin-4-amine CAS 40172-82-5
| CAS No. | 40172-82-5 |
| Molecular Formula | C13H10N4 |
| Molecular Weight | 222.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Pyridin-2-yl)quinazolin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(Pyridin-2-yl)quinazolin-4-amine (CAS 40172-82-5) is a high-purity analytical reference standard with the molecular formula C13H10N4 and a molecular weight of 222.25 g/mol.
The molecular framework of 2-(Pyridin-2-yl)quinazolin-4-amine (C13H10N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10N4 |
| Molecular Weight | 222.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 4 |
Related Pyridin Standards
- 6-(Pyridin-4-yl)quinazolin-2-amine (CAS 1008505-37-0)
- 4-(Pyridin-4-yl)phthalazin-1-amine (CAS 139328-94-2)
- 2-(Pyridin-3-yl)-4-(1H-pyrrol-1-yl)pyrimidine (CAS 439108-38-0)
- 2-(Pyridin-3-yl)quinazolin-4-amine (CAS 273408-90-5)
- 3-(5-(Pyridin-4-yl)-1H-pyrazol-3-yl)pyridine (CAS 32827-37-5)
- 5-Phenyl-2-(pyridin-3-yl)oxazole (CAS 106590-21-0)
- 4-(Pyridin-3-yl)-1H-indole-3-carbaldehyde (CAS 108378-88-7)
- 4-(Pyridin-4-yl)-1H-indole-3-carbaldehyde (CAS 108378-89-8)
Recommended Standards
- 1-Methoxy-4-((1R,2R)-2-(trifluoromethyl)cyclopropyl)benzene (CAS 900779-69-3)
- (E)-7-styryl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 91823-31-3)
- (2Z)-2-Amino-3-[(E)-[(2E)-3-phenylprop-2-en-1-ylidene]amino]but-2-enedinitrile (CAS 55083-91-5)
- 2,2,2-trifluoro-1-(2,4,5-trimethylphenyl)ethanone (CAS 220675-88-7)
- 301820-48-4 5-(2-Hydroxybenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one MFCD28505125 (CAS 301820-48-4)
- (6-Chloro-5-methylpyridin-3-yl)methylamine (CAS 1256824-90-4)
- (R)-Oxybutynin Chloride (CAS 1207344-05-5)
- (2E)-1-(2-Methylpiperazin-1-yl)-3-phenylprop-2-en-1-one (CAS 1240590-90-2)
- N-1-Z-1,6-diaminohexane (CAS 66095-18-9)
- Methyl 4-(1h-imidazol-1-yl)-2-methyl-2-(methylamino)pentanoate (CAS 1343573-94-3)
- 2-Chloro-3,5-dibromo-4-fluorotoluene (CAS 1160574-79-7)
- 5-Oxo-1-(3-oxo-1,3-dihydro-2-benzofuran-1-yl)-D-proline (CAS 1217542-54-5)
- Cilastatin Impurity 37 (CAS CATO-C4X-196037)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
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