2-Iodo-3-hydroxypyridine CAS 40263-57-8
| CAS No. | 40263-57-8 |
| Molecular Formula | C5H4INO |
| Molecular Weight | 221.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Iodo-3-hydroxypyridine.
CATO supplies 2-Iodo-3-hydroxypyridine (CAS 40263-57-8), a certified reference material (molecular formula C5H4INO, MW 221.00 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, iodine substitution, 2-Iodo-3-hydroxypyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4INO |
| Molecular Weight | 221.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-Iodo-1H-pyridin-2-one (CAS 111079-46-0)
- 2-Iodo-1H-pyrrole-3-carbaldehyde (CAS 35302-92-2)
- 3-Iodo-1H-pyrrole-2-carbaldehyde (CAS 40566-07-2)
- 4-Iodo-1H-pyrrole-3-carbaldehyde (CAS 35302-93-3)
- 5-Iodo-1H-pyrrole-2-carbaldehyde, 97% (CAS 40566-13-0)
- 5-Iodo-1H-pyrrole-3-carbaldehyde (CAS 35302-91-1)
- 4-Iodo-1H-pyrazole-3-carbaldehyde (CAS 1259224-01-5)
- 5-Iodo-1H-imidazole-4-carbaldehyde (CAS 189014-12-8)
Recommended Standards
- 3-Bromo-2,6-difluorobenzaldehyde (CAS 398456-82-1)
- 2-Bromo-4,5-difluorobenzaldehyde (CAS 476620-54-9)
- 3-Bromo-4-fluorobenzoyl fluoride (CAS 78239-65-3)
- 2-Bromo-3,6-difluorobenzaldehyde, 97% (CAS 934987-26-5)
- 4-Bromo-3-chloropicolinamide (CAS 1805017-96-2)
- 3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1h-pyrazole (CAS 1217340-87-8)
- 1-BRomo-3-methyl-5-(propan-2-yloxy)benzene (CAS 1268150-29-3)
- (3S,4R)-4-(p-tolyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1049728-10-0)
- (S)-1-((S)-3-(1H-Imidazol-4-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanoyl)piperidine-3-carboxamide (CAS 88466-78-8)
- 1-Ethyl-N-(3-methoxybenzyl)piperidin-4-amine (CAS 1119450-01-9)
- 2,2-Difluoro-2-(p-tolyl)acetamide (CAS 875898-85-4)
- 3,6-Bis(hexylthio)phthalonitrile (CAS 344453-43-6)
- Hydroxyzine Impurity B Hydrochloride salt (CAS 1263283-80-2)
- TRAF6 Peptide trifluoroacetate salt (CAS 852805-92-6)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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