4’-Fluoro-2-hydroxyacetophenone CAS 403-31-6
| CAS No. | 403-31-6 |
| Molecular Formula | C8H7FO2 |
| Molecular Weight | 154.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4’-Fluoro-2-hydroxyacetophenone (CAS 403-31-6), a certified reference material (molecular formula C8H7FO2, MW 154.14 g/mol) for analytical method development and quality control.
4’-Fluoro-2-hydroxyacetophenone (C8H7FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4’-Fluoro-2-hydroxyacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7FO2 |
| Molecular Weight | 154.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-3-methoxybenzaldehyde (CAS 103438-88-6)
- 2-Fluoro-5-methoxybenzaldehyde (CAS 105728-90-3)
- 6-Fluoro-2-hydroxy-3-methylbenzaldehyde (CAS 1067225-48-2)
- 4-Fluoro-N'-hydroxybenzimidamide (CAS 1164246-18-7)
- 7-fluoro-2,3-dihydrobenzofuran-4-ol (CAS 1232774-17-2)
- 3-Fluoro-2-hydroxy-4-methylbenzaldehyde (CAS 1283718-64-8)
- 3-Fluoro-5-(hydroxymethyl)benzaldehyde (CAS 1289164-74-4)
- (Z)-3-Fluoro-N'-hydroxybenzene-1-carboximidamide 1319746-46-7 C7H7FN2O Z9634 (CAS 1319746-46-7)
Recommended Standards
- 3-Sulfopropanoic acid (CAS 44826-45-1)
- 4-Amino-2-fluorobenzamide (CAS 609783-45-1)
- 3-Fluorophenyl Acetate (CAS 701-83-7)
- 4-Amino-3-fluorobenzamide (CAS 609783-62-2)
- 1-(isocyanatomethyl)-2-(trifluoromethyl)benzene (CAS 55204-86-9)
- 2-(3,5-Dimethyl-1-(pyridin-2-yl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1177355-64-4)
- N-Benzyl-N-(4-methyloxazol-2-yl)hexanamide (CAS 57068-71-0)
- (8-Hydroxyquinolin-7-yl)boronic acid (CAS 1093231-10-7)
- 4-Ethoxy-4-iodobenzophenone (CAS 951884-62-1)
- (2-methyl-2H-indazol-6-yl)methanol (CAS 1159511-53-1)
- N-Benzyl-2-hydroxy-N,N-dimethylethanaminium chloride (CAS 7221-40-1)
- 11H-Dibenzo[b,e][1,4]dioxepin-2-amine hydrochloride (CAS 1824548-00-6)
- 8-Propyl-8-azabicyclo[3.2.1]octan-3-ol (CAS 859990-64-0)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com