Methyl 4-fluorobenzoate CAS 403-33-8
| CAS No. | 403-33-8 |
| Molecular Formula | C8H7FO2 |
| Molecular Weight | 154.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-fluorobenzoate.
Methyl 4-fluorobenzoate (CAS 403-33-8) is a high-purity analytical reference standard with the molecular formula C8H7FO2 and a molecular weight of 154.14 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Methyl 4-fluorobenzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 154.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 4-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7FO2 |
| Molecular Weight | 154.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Methyl Standards
- Methyl 2-Fluorobenzoate (CAS 394-35-4)
- Methyl 3-fluorobenzoate, 98% (CAS 455-68-5)
- Ethyl 2-Fluorobenzoate (CAS 443-26-5)
- Ethyl 3-Fluorobenzoate (CAS 451-02-5)
- Ethyl 4-fluorobenzoate (CAS 451-46-7)
- Benzyl 4-fluorobenzoate (CAS 59986-44-6)
- Sodium 3-fluorobenzoate (CAS 499-57-0)
- Sodium 4-fluorobenzoate (CAS 499-90-1)
Recommended Standards
- N-(6-Fluoropyridin-2-yl)acetamide (CAS 258343-71-4)
- N-Nitroso-N-methyl-4-fluoroaniline (CAS 937-25-7)
- Hexanoic acid, 4-hydroxy-, sodium salt (1:1) (CAS 85873-09-2)
- Sodium 4-hydroxy-4-methylpentanoate (CAS 581099-89-0)
- 3,8-Difluoroquinoline (CAS 1781159-07-6)
- 1-(6-Methoxypyridazin-3-yl)-N-methylmethanamine (CAS 1248013-02-6)
- n-Phenethyl-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 304888-44-6)
- 1-((4-Bromobenzyl)oxy)-2-chloro-4-fluorobenzene (CAS 1275853-29-6)
- 3-Chloro-1-methyl-1H-pyrazole-4-sulfonamide (CAS 101457-06-1)
- 2-(4-Bromothiophen-3-yl)-2-methylpropanoic acid (CAS 1528989-30-1)
- MPC-3100 (CAS 958025-66-6)
- rac-methyl (3R,4R)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidine-3-carboxylate (CAS 1909294-26-3)
- (5-Fluoro-2-methoxyphenyl)methanesulfonyl chloride (CAS 1505586-29-7)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
Why CATO?
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