3-Methyl-2-((trimethylsilyl)oxy)butanenitrile CAS 40326-16-7
| CAS No. | 40326-16-7 |
| Molecular Formula | C8H17NOSi |
| Molecular Weight | 171.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methyl-2-((trimethylsilyl)oxy)butanenitrile.
3-Methyl-2-((trimethylsilyl)oxy)butanenitrile (CAS 40326-16-7) is a high-purity analytical reference standard with the molecular formula C8H17NOSi and a molecular weight of 171.31 g/mol.
The molecular framework of 3-Methyl-2-((trimethylsilyl)oxy)butanenitrile (C8H17NOSi) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H17NOSi |
| Molecular Weight | 171.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-Methyl-2-((trimethylsilyl)oxy)butanenitrile (CAS 25438-34-0)
- 1-(Trimethylsilyl)-2-piperidinone 3553-93-3 N-Trimethylsilyl-2-piperidinone Trimethylsilyl Valerolactam (CAS 3553-93-3)
- 2-Trimethylsilyl-n-tert-butylacetaldimine (CAS 73198-78-4)
- Bis(trimethylsilyl)acetylene (CAS 14630-40-1)
- 6-(Trimethylsilyl)hex-5-yn-1-ol (CAS 103437-52-1)
- 4-((Trimethylsilyl)oxy)pent-3-en-2-one (CAS 13257-81-3)
- 3-Methyl-1-trimethylsilyl-1-pentyn-3-ol(+/-) (CAS 17889-43-9)
- (Trimethylsilyl)methyl methacrylate (CAS 18269-97-1)
Recommended Standards
- 65894-82-8 X9G2EIF1QQ 2-(2-Butyl)-4,5-dimethyl-3-thiazoline 2-sec-Butyl-4,5-dimethyl-2,5-dihydrothiazole Thiazole, 2,5-dihydro-4,5-dimethyl-2-(1-methylpropyl)- 3-Thiazoline, 2-sec-butyl-4,5-dimethyl- 2-sec-Butyl-4,5-dimethyl thiazoline 2-sec-Butyl-4,5-dimethyl-3-thiazoline 2,5-Dihydro-4,5-dimethyl-2-(1-methylpropyl)thiazole EINECS 265-968-0 FEMA No. 3619 UNII-X9G2EIF1QQ (CAS 65894-82-8)
- 2,4,4-Trimethyl-N-propylpentan-2-amine (CAS 101495-75-4)
- 1-Benzothiophen-2ylmethylamine 1-benzothiophen-2-ylmethylamine 2-(aminomethyl)benzo[b]thiophene c-benzo[b]thiophen-2-yl-methylamine 1-benzothiophene-2-yl methylamine 6314-43-8 (CAS 6314-43-8)
- n-Isopentyl-3-methylpentan-2-amine (CAS 1042621-00-0)
- Methyl 3,4,5-trichlorobenzoate (CAS 114821-66-8)
- N-(3-Cyano-6-methanesulfonyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,2-diphenylacetamide (CAS 1148027-15-9)
- PG 01 (CAS 853138-65-5)
- 2-(Sec-butoxy)-5-iodoaniline (CAS 1484302-65-9)
- 3,5-Dibromo-2-chloro-6-methoxypyridine (CAS 2432849-11-9)
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- Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate (CAS 1129683-92-6)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
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