4-{[(trimethylsilyl)oxy]methyl}aniline CAS 403613-26-3
| CAS No. | 403613-26-3 |
| Molecular Formula | C10H17NOSi |
| Molecular Weight | 195.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-{[(trimethylsilyl)oxy]methyl}aniline (CAS 403613-26-3), a certified reference material (molecular formula C10H17NOSi, MW 195.33 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, 4-{[(trimethylsilyl)oxy]methyl}aniline is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 195.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17NOSi |
| Molecular Weight | 195.33 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related trimethylsilyl Standards
- 2-Methyl-4-[2-(trimethylsilyl)ethynyl]-1,3-thiazole (CAS 329203-85-2)
- 3-(Trimethylsilyl)isonicotinic acid (CAS 112266-47-4)
- Trimethylsilyl picolinate (CAS 17881-49-1)
- 5-(Trimethylsilyl)picolinic acid (CAS 2879222-38-3)
- 2-[(Trimethylsilyl)ethynyl]aniline (CAS 103529-16-4)
- 2-(Trimethylsilyl)ethyl 2-chloroacetate (CAS 100297-89-0)
- 1,4-Bis(trimethylsilyl)buta-1,3-diyne (CAS 4526-07-2)
- 2-Phenyl-2-(trimethylsilyl)ethanol (CAS 122760-31-0)
Recommended Standards
- 2-Ethoxy-3-(trimethylsilyl)pyridine (CAS 782479-88-3)
- n-Cyclopentylcyclooctanamine (CAS 1019481-61-8)
- 4-(Methoxy(trimethylsilyl)methyl)pyridine (CAS 138761-47-4)
- N-cyclopentyl-4-ethylcyclohexan-1-amine (CAS 1019579-70-4)
- (S)-N-Isopropyl-1-methylpiperidin-3-amine (CAS 1354003-92-1)
- tert-Butyl (R)-3-hydroxy-1-oxo-8-azaspiro[4.5]decane-8-carboxylate (CAS 1801767-38-3)
- 2,2-Dichloro-1(2H)-acenaphthylenone (CAS 13152-85-7)
- (R)-1-(pyridin-4-yl)propan-1-amine (CAS 1213012-47-5)
- (r)-4-(1-Amino-2-hydroxyethyl)-3-fluorophenol (CAS 1213699-15-0)
- (R)-3-(1-Aminoethyl)-5-(difluoromethyl)-4-fluoroaniline (CAS 2789706-30-3)
- ((3AS,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2-phenyltetrahydrofuro[3,4-d][1,3,2]dioxaborol-4-yl)methyl 4-methylbenzenesulfonate (CAS 23312-76-7)
- tert-Butyl N-[(3S,5S)-5-fluoropiperidin-3-yl]carbamate (CAS 1593969-81-3)
- 1-(4-Methylbenzyl)-1H-pyrrole (CAS 94054-40-7)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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