(3R)-1-Methylpyrrolidin-3-amine dihydrochloride CAS 403712-80-1

Description

The occurrence of (3R)-1-Methylpyrrolidin-3-amine dihydrochloride is closely related to chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(3R)-1-Methylpyrrolidin-3-amine dihydrochloride (CAS 403712-80-1), molecular formula C5H12N2HCl and molecular weight 136.62 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (3R)-1-Methylpyrrolidin-3-amine dihydrochloride (C5H12N2HCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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