1,2-Diphenylhydrazine hydrochloride CAS 40391-77-3
| CAS No. | 40391-77-3 |
| Molecular Formula | C12H12N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,2-Diphenylhydrazine hydrochloride (CAS 40391-77-3), molecular formula C12H12N2HCl and molecular weight 220.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 1,2-Diphenylhydrazine hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 220.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1,2-Diphenylhydrazine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N2 HCl |
| Molecular Weight | 220.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Diphenylhydrazine Standards
- 2,2-Diphenylhydrazine-1-carbothioamide (CAS 13207-45-9)
- 1,1-Diphenylhydrazine xhydrochloride (CAS 29666-92-0)
- 1,1-Diphenylhydrazine Hydrochloride (CAS 530-47-2)
- 1,1-Diphenylhydrazine (CAS 530-50-7)
- N',2-diphenylhydrazine-1-carbothiohydrazide (CAS 622-03-7)
- 1,2-Diphenylhydrazine diphenyl-d10 (CAS 93951-92-9)
Recommended Standards
- 3-(3,5-Dichlorophenyl)-2-thioxo-1,3-thiazolidin-4-one (CAS 29219-14-5)
- 3,6-Diamino-2-(difluoromethyl)isonicotinonitrile (CAS 1806811-58-4)
- 4-Amino-3,5-dinitrobenzenesulfonic acid (CAS 98139-22-1)
- Benzofuro[4,5-c]isoxazole (CAS 64399-46-8)
- Lopinavir EP Impurity G (CAS CATO-C4X-16827)
- (2-(Tetrahydro-2H-thiopyran-4-yl)thiazol-4-yl)methanol (CAS 1478716-69-6)
- 2-Chloro-4-(difluoromethyl)thiophen-3-amine (CAS 2732241-93-7)
- 7-Keto Glycodeoxycholic Acid (CAS CATO-C4X-116034)
- 1-(Aminomethyl)naphthalen-2-ol (CAS 5386-23-2)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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