Dexmedetomidine Impurity 47 CAS 40420-17-5
| CAS No. | 40420-17-5 |
| Molecular Formula | C10H14O |
| Molecular Weight | 150.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dexmedetomidine Impurity 47 is closely related to a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dexmedetomidine Impurity 47 (CAS 40420-17-5, C10H14O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dexmedetomidine Impurity 47 (C10H14O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexmedetomidine Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H14O |
| Molecular Weight | 150.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
Related Dexmedetomidine Standards
- Dexmedetomidine Impurity 1 (CAS 60907-90-6)
- Dexmedetomidine Impurity 17 (CAS 33967-19-0)
- Dexmedetomidine impurity 62 (CAS 19447-06-4)
- Dexmedetomidine impurity 63 (CAS 32917-52-5)
- Dexmedetomidine impurity 64 (CAS 5379-18-0)
- Dexmedetomidine Impurity 26 (CAS 603-79-2)
- Dexmedetomidine Impurity 31 (CAS 2142-71-4)
- Dexmedetomidine Impurity 51 (CAS 13651-55-3)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com