2-Benzylidene-1,3-dioxo-2,3-dihydro-1H-indene-5-carboxylic acid CAS 40462-12-2
| CAS No. | 40462-12-2 |
| Molecular Formula | C17H10O4 |
| Molecular Weight | 278.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Benzylidene-1,3-dioxo-2,3-dihydro-1H-indene-5-carboxylic acid (CAS 40462-12-2), a certified reference material (molecular formula C17H10O4, MW 278.26 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, 2-Benzylidene-1,3-dioxo-2,3-dihydro-1H-indene-5-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H10O4 |
| Molecular Weight | 278.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
Related Benzylidene Standards
- 2-Benzylidene-6-((5-methylfuran-2-yl)methylene)cyclohexanone (CAS 880098-64-6)
- (Z)-4-Benzylidene-3-(phenoxymethyl)isoxazol-5(4H)-one (CAS 112082-71-0)
- 4-Benzylidene-2-(4-methoxyphenyl)oxazol-5(4H)-one (CAS 34108-13-9)
- (5E)-5-Benzylidene-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one (CAS 145693-86-3)
- 5-Benzylidene-3-phenyl-2-thioxoimidazolidin-4-one (CAS 32832-07-8)
- 4-Benzylidene-1-methylpyrrolidine-2,3-dione (CAS 35921-36-9)
- 4-Benzylidene-2-(styryl)oxazol-5(4H)-one (CAS 40913-25-5)
- 1-Benzylidene-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 823234-53-3)
Recommended Standards
- 2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetic acid (CAS 956742-88-4)
- 2-Methyl-1H-chromeno[2,3-b][1,6]naphthyridine-1,11(2H)-dione (CAS 240799-42-2)
- 2-[(2H-1,3-Benzodioxol-5-yl)methylidene]-2,3-dihydro-1H-indene-1,3-dione (CAS 29874-34-8)
- 3-(1H-Benzo[d]imidazol-2-yl)-7-hydroxy-2H-chromen-2-one (CAS 68482-66-6)
- basimglurant (CAS 802906-73-6)
- TERT-BUTYL 4-(1,2-DIHYDRO-6-METHOXY-2-OXOBENZO[D]IMIDAZOL-3-YL)PIPERIDINE-1-CARBOXYLATE (CAS 1951441-72-7)
- 4-(3,4-Dimethylphenyl)pyrrolidine-3-carboxylic acid (CAS 1342529-53-6)
- [9,9'-Bianthracene]-10-carbaldehyde (CAS 77802-21-2)
- Morpholin-3-yl(thiomorpholino)methanone (CAS 1469033-82-6)
- 2-Methyl-2-phenylpent-4-enenitrile (CAS 104367-49-9)
- Ethyl7-chloroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1204501-38-1)
- 2-Methyl-1-[4-(trifluoromethyl)phenyl]propan-2-amine hydrochloride (CAS 1081-78-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-4-yl)propanoic acid (CAS 553643-52-0)
- Vialox Peptide(Pentapeptide-3) diacetate (CAS 725232-44-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com