6-Chloro-3-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione maleate CAS 4052-18-0
| CAS No. | 4052-18-0 |
| Molecular Formula | C21H22Cl2N4O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-3-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione maleate.
6-Chloro-3-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione maleate (CAS 4052-18-0), molecular formula C21H22Cl2N4O2C4H4O4 and molecular weight 549.40 g/mol, is a CATO reference standard with documented purity and traceability.
6-Chloro-3-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione maleate (C21H22Cl2N4O2C4H4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-3-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione maleate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H22Cl2N4O2 C4H4O4 |
| Molecular Weight | 549.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- {3-[(Benzylthio)methyl]phenyl}{4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone (CAS 260781-45-1)
- (R)-1-(1-Chloroethyl)-3-nitrobenzene (CAS 2137086-61-2)
- Ethyl 4-(2-ethoxy-2-oxoethyl)-3-nitrobenzoate (CAS 891782-57-3)
- (2,4-Dihydroxyphenyl)boronic acid (CAS 1312943-20-6)
- 4,6-Difluoro-1-methyl-1H-indazole-5-carboxylic acid (CAS 1329166-90-6)
- (2R,3R,4R,5R)-2-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate (CAS 130-50-7)
- 6-chlorobenzofuran-7-amine (CAS 379230-43-0)
- 4-(5-chloropyridin-2-yl)-4-oxobutanoic acid (CAS 1542589-72-9)
- N-((2,6-dichloropyrimidin-4-yl)methyl)ethanamine (CAS 1289386-58-8)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
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