2-(4-Fluorophenyl)ethanesulfonyl chloride CAS 405219-34-3
| CAS No. | 405219-34-3 |
| Molecular Formula | C8H8ClFO2S |
| Molecular Weight | 222.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(4-Fluorophenyl)ethanesulfonyl chloride (CAS 405219-34-3), molecular formula C8H8ClFO2S and molecular weight 222.66 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-Fluorophenyl)ethanesulfonyl chloride (C8H8ClFO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(4-Fluorophenyl)ethanesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO2S |
| Molecular Weight | 222.66 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 2-(3-Fluorophenyl)ethanesulfonyl chloride (CAS 728919-65-1)
- 1-[(4-fluorophenyl)methyl]-3,3-dimethylpiperazine (CAS 1226207-80-2)
- 1-(1-(4-Fluorophenyl)propyl)piperazine (CAS 516447-25-9)
- 1-Ethyl-4-[(4-fluorophenyl)methyl]piperazine (CAS 864389-15-1)
- 2-(3-Fluorophenyl)-2-(1-piperidyl)ethylamine (CAS 933706-87-7)
- 2-(4-(4-Fluorophenyl)piperidin-1-yl)ethan-1-amine (CAS 944907-01-1)
- 2-(4-Fluorophenyl)-2-(1-piperidyl)ethylamine (CAS 876710-67-7)
- (T-4)-(4-Fluorophenyl)[2-[(hydroxy-κO)methyl]-2-methyl-1,3-propanediolato(3-)-κO1,κO3]-Borate potassium (CAS 1014716-92-7)
Recommended Standards
- 2-Chloro-1-fluoro-4-((methylsulfonyl)methyl)benzene (CAS 886498-20-0)
- 2-(2-Fluoro-phenyl)-ethanesulfonyl chloride (CAS 728919-67-3)
- 2-Chloro-6-fluorobenzylmethylsulfone (CAS 20018-05-7)
- 1-Chloro-2-fluoro-3-((methylsulfonyl)methyl)benzene (CAS 886498-11-9)
- 2-{1-[(1H-1,2,4-triazol-3-yl)amino]ethylidene}-2,3-dihydro-1H-indene-1,3-dione (CAS 59876-69-6)
- 7-Carbamoylbenzofuran-2-carboxylic acid (CAS 2416233-08-2)
- 4-Bromo-1-methyl-2-(pentyloxy)benzene (CAS 1309932-69-1)
- Methyl 2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 887408-51-7)
- 1-(3-Cyclopropyl-1-methyl-1h-1,2,4-triazol-5-yl)-2-methylpropan-1-amine (CAS 1342132-53-9)
- N-MEthyl-6-piperidin-3-ylnicotinamide dihydrochloride (CAS 1858255-34-1)
- 1-(6-(4-Methyl-1h-imidazol-1-yl)pyridin-3-yl)ethan-1-one (CAS 810662-41-0)
- 1-Butyl-4-iodo-3-methyl-1H-pyrazol-5-amine (CAS 1248805-32-4)
- Erythromycin Stearate (CAS 643-22-1)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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