2,5-Dichloro-3-nitropyridin-4-amine CAS 405230-91-3
| CAS No. | 405230-91-3 |
| Molecular Formula | C5H3Cl2N3O2 |
| Molecular Weight | 208.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,5-Dichloro-3-nitropyridin-4-amine (CAS 405230-91-3), a certified reference material (molecular formula C5H3Cl2N3O2, MW 208.00 g/mol) for analytical method development and quality control.
2,5-Dichloro-3-nitropyridin-4-amine (C5H3Cl2N3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2,5-Dichloro-3-nitropyridin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl2N3O2 |
| Molecular Weight | 208.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 3,5-Dichloro-6-hydroxypicolinic acid (CAS 103997-22-4)
- 2,4-Dichloro-6-methyl-5-nitropyrimidine (CAS 13162-26-0)
- 4,6-Dichloro-2-methyl-5-nitropyrimidine (CAS 13162-43-1)
- 2,3-Dichloro-5-nitrophenol (CAS 1806356-80-8)
- 2,6-Dichloro-3-hydroxyisonicotinic acid (CAS 185422-96-2)
- 3,4-Dichloro-5-nitropyridin-2-amine (CAS 1936288-61-7)
- 2,3-Dichloro-4-nitrophenol (CAS 59384-57-5)
- 2,4-Dichloro-3-nitrophenol (CAS 38902-87-3)
Recommended Standards
- 2,4-Dichloro-6-nitrophenol (CAS 609-89-2)
- 2,5-Dichloro-4-nitrophenol (CAS 5847-57-4)
- 2,4-Dichloro-5-nitrophenol (CAS 39489-77-5)
- 2,6-Dichloro-4-nitraminopyridine (CAS 2587-03-3)
- 4-(Dimethyl-1h-1,2,4-triazol-1-yl)-2-methylbenzaldehyde (CAS 1247108-88-8)
- GSK-8814, >98% (HPLC) (CAS 1997369-78-4)
- 3,5-Dichloro-3-(4-methylphenyl)propiophenone (CAS 898769-31-8)
- N-(3-(5,6-diethyl-4-oxo-1,4-dihydropyrimidin-2-yl)-4-propoxyphenyl)-2-(4-methylpiperazin-1-yl)acetamide (CAS 1229018-87-4)
- (-)-<I>N</I>-(1(<I>R</I>)-phenylethyl)-1-azabicyclo[2.2.2]octyl-3(<I>S </I>)-amine dihydrochloride (CAS 128311-06-8)
- 3-benzyl-2-mercapto-5-methyl-3,5-dihydro-4H-imidazol-4-one (CAS 36017-41-1)
- Isobutyl hexyl oxalate (CAS 959067-92-6)
- Diloxanide (CAS 579-38-4)
- 1,3-Dimethylquinolin-1-ium (CAS 73027-87-9)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
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