(e)-2-(3-Chlorophenyl)ethene-1-sulfonamide CAS 405262-52-4
| CAS No. | 405262-52-4 |
| Molecular Formula | C8H8ClNO2S |
| Molecular Weight | 217.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(e)-2-(3-Chlorophenyl)ethene-1-sulfonamide (CAS 405262-52-4), molecular formula C8H8ClNO2S and molecular weight 217.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, (e)-2-(3-Chlorophenyl)ethene-1-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 217.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (e)-2-(3-Chlorophenyl)ethene-1-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2S |
| Molecular Weight | 217.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related e Standards
- 2-(4-Chlorophenyl)ethene-1-sulfonamide (CAS 64984-11-8)
- N-(4-Chlorophenyl)ethenesulfonamide (CAS 89978-95-0)
- 2-(5-(4-Chlorophenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 134161-76-5)
- (2-Chlorophenyl)(pyridin-2-yl)methanone (CAS 1694-57-1)
- (2-Chlorophenyl)(pyridin-3-yl)methanone (CAS 42374-49-2)
- (3-Chlorophenyl)(pyridin-4-yl)methanone (CAS 62246-94-0)
- 2-(3-(4-Chlorophenyl)-1H-pyrazol-1-yl)acetonitrile (CAS 959573-11-6)
- 2-(4-Chlorophenyl)isonicotinaldehyde (CAS 959265-66-8)
Recommended Standards
- (2-Chloroethyl)(4-nitrophenyl)sulfane (CAS 5535-73-9)
- (Z)-2-Chloro-2-phenylethenesulfonamide (CAS 64984-30-1)
- (2-Chloro-1,3-thiazol-5-yl)methyl cyclopropanecarboxylate (CAS 341967-81-5)
- [(2-Chloro-6-fluorophenyl)methyl](2-methoxyethyl)amine (CAS 827328-46-1)
- 6-Hydroxy-1H-indole-4-carbonitrile (CAS 1082040-53-6)
- 2,4-Dinitrophenyl 2-Deoxy-2-fluoro-b-D-galactoside (CAS 143716-62-5)
- 2-(3-Ethoxyphenyl)ethan-1-amine (CAS 76935-76-7)
- 2-[({[2-(morpholin-4-yl)-5-(morpholine-4-sulfonyl)phenyl]carbamoyl}methyl)sulfanyl]pyridine-3-carboxylic acid (CAS 721406-33-3)
- 2-[benzyl(methyl)amino]butanoic acid hydrochloride (CAS 1803560-77-1)
- 9,9-Bis(3,4-dicarboxyphenyl)fluorene dianhydride (CAS 135876-30-1)
- 5-Bromo-2-chlorobicyclo[4.2.0]Octa-1,3,5-triene-7-carboxylic acid (CAS 1135490-73-1)
- Methyl 4,5-Dimethylpyrrole-2-carboxylate (CAS 33317-03-2)
- UDP-D-glucose disodium salt (CAS 117756-22-6)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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