N-(2-Hydroxyethyl)-2H-pyrazole-3-carboxamide CAS 405278-69-5
| CAS No. | 405278-69-5 |
| Molecular Formula | C6H9N3O2 |
| Molecular Weight | 155.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(2-Hydroxyethyl)-2H-pyrazole-3-carboxamide (C6H9N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
N-(2-Hydroxyethyl)-2H-pyrazole-3-carboxamide (CAS 405278-69-5), molecular formula C6H9N3O2 and molecular weight 155.15 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(2-Hydroxyethyl)-2H-pyrazole-3-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2 |
| Molecular Weight | 155.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(1-(2-Hydroxyethyl)-1H-pyrazol-5-yl)formamide (CAS 122589-40-6)
- 5-(2-Hydroxyethyl)-1H-pyrazole-3-carboxamide (CAS 1312205-25-6)
- n-(2-Hydroxyethyl)-1h-imidazole-5-carboxamide (CAS 1493308-12-5)
- 3-(1-Hydroxyethyl)-4-methyl-1H-pyrrole-2,5-dione (CAS 173418-77-4)
- 1-(2-hydroxyethyl)-1H-pyrazole-4-carboxamide (CAS 1849283-80-2)
- 1-(5-(1-Hydroxyethyl)isoxazol-3-yl)ethanone (CAS 301168-23-0)
- 2-((2-Hydroxyethyl)amino)pyrimidin-4-ol (CAS 459218-68-9)
- 2-Hydroxyethyl 1H-pyrrole-2-carboxylate (CAS 668987-22-2)
Recommended Standards
- methyl trans-3-azidocyclobutanecarboxylate (CAS 79584-09-1)
- N-(2-Hydroxyethyl)-4H-pyrazole-3-carboxamide (CAS 446053-75-4)
- Methyl 5-ethylisoxazole-4-carboxylate (CAS 954229-90-4)
- N-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)acetamide (CAS 99357-28-5)
- 5-Bromo-6-chloro-3-iodopyrazin-2-amine (CAS 2090186-99-3)
- 2-(Cyclohexylamino)-N'-(diphenylmethylidene)propanehydrazide (CAS 321848-39-9)
- 3,5-Dibromo-1-octyl-1H-1,2,4-triazole (CAS 1240572-77-3)
- n'-Hydroxy-2-(isopropylamino)acetimidamide (CAS 1344802-60-3)
- 3-(Trifluoromethyl)-6,7-dihydro-5h-pyrrolo[3,4-b]pyridine dihydrochloride (CAS 2212669-82-2)
- 1-Ethyl-n,n-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide (CAS 875163-22-7)
- 3-(Methanesulfonylmethyl)benzoic acid (CAS 261924-94-1)
- Nintedanib Impurity 25 (CAS 262368-25-2)
- Methyl 2,3,5-trichloro-6-hydroxybenzoate (CAS 111217-18-6)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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