8-Methyl-2(1H)-quinolinone CAS 4053-36-5
| CAS No. | 4053-36-5 |
| Molecular Formula | C10H7NO |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 157.17 g/mol gives 8-Methyl-2(1H)-quinolinone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Methyl-2(1H)-quinolinone (CAS 4053-36-5), molecular formula C10H7NO and molecular weight 157.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Methyl-2(1H)-quinolinone (C10H7NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Methyl-2(1H)-quinolinone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7NO |
| Molecular Weight | 157.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Recommended Standards
- 8-Isoquinolinecarboxaldehyde (CAS 787615-01-4)
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