4-(4-bromophenyl)-1H-pyrazol-3-amine CAS 40545-64-0
| CAS No. | 40545-64-0 |
| Molecular Formula | C9H8BrN3 |
| Molecular Weight | 238.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-bromophenyl)-1H-pyrazol-3-amine (C9H8BrN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(4-bromophenyl)-1H-pyrazol-3-amine (CAS 40545-64-0), molecular formula C9H8BrN3 and molecular weight 238.08 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8BrN3 |
| Molecular Weight | 238.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related bromophenyl Standards
- 4-(4-bromophenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 1017246-65-9)
- 3-(2-Bromophenyl)-4-methyl-4H-1,2,4-triazole (CAS 1034734-64-9)
- 3-(2-Bromophenyl)-5-methyl-4h-1,2,4-triazole (CAS 1094653-15-2)
- 3-(3-Bromophenyl)-5-methyl-1h-1,2,4-triazole (CAS 1152849-67-6)
- 1-(2-Bromophenyl)-1h-pyrazol-4-amine (CAS 1153039-45-2)
- 1-(3-Bromophenyl)-1H-pyrazol-4-amine (CAS 1155573-22-0)
- 1-(2-Bromophenyl)-1h-pyrazol-5-amine (CAS 1155574-39-2)
- 3-(3-Bromophenyl)-1H-pyrazol-4-amine (CAS 1171492-86-6)
Recommended Standards
- 4-(4-Bromo-1H-pyrazol-1-yl)aniline (CAS 681441-17-8)
- 4-(4-Bromophenyl)-1H-pyrazol-5-amine (CAS 57999-08-3)
- 4-(3-Bromophenyl)-4-oxobutanenitrile (CAS 884504-63-6)
- 4-(4-Bromophenyl)-2-methyloxazole (CAS 22091-49-2)
- 5-Cyanobenzofuran-2-carboxylic Acid (CAS 84102-75-0)
- 5-Oxo-5-(phenethylamino)pentanoic acid (CAS 119627-14-4)
- (2,2-diethoxyethyl)benzene (CAS 6314-97-2)
- (2-Chlorophenyl)(3-methoxyphenyl)methanone (CAS 890098-07-4)
- Perampanel Impurity 17 (CAS 172732-52-4)
- FIPI (CAS 939055-18-2)
- Trans-4-((6,7-dimethoxyquinoxalin-2-yl)amino)cyclohexanol (CAS 216699-96-6)
- 3,3-Dimethyl-1-(3-nitrophenyl)azetidin-2-one (CAS 34449-03-1)
- Ethyl 2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylate (CAS 1425335-18-7)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com