2-(4-Bromo-phenyl)-4,6-dichloro-quinazoline CAS 405933-98-4
| CAS No. | 405933-98-4 |
| Molecular Formula | C14H7BrCl2N2 |
| Molecular Weight | 354.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(4-Bromo-phenyl)-4,6-dichloro-quinazoline (CAS 405933-98-4), molecular formula C14H7BrCl2N2 and molecular weight 354.03 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, 2-(4-Bromo-phenyl)-4,6-dichloro-quinazoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 354.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H7BrCl2N2 |
| Molecular Weight | 354.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 2-(4-Bromo-phenyl)-4,7-dichloro-quinazoline (CAS 405933-94-0)
- 6-Bromo-4-chloro-2-(4-chloro-phenyl)-quinazoline (CAS 885277-66-7)
- Ethyl 3-bromo-4-(3,4-dichlorophenyl)-4-oxobutanoate (CAS 35158-45-3)
- 2-Bromo-1-(4'-bromo-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 94512-73-9)
- 2-Bromo-1-(4-bromophenyl)-2-phenylethan-1-one (CAS 24567-06-4)
- N-(4-bromo-2-methylphenyl)-2-iodoacetamide (CAS 1174495-86-3)
- 5-Bromo-N-ethyl-2-iodobenzamide (CAS 1295978-68-5)
- Methyl 7-bromo-2,4-dichloro-8-fluoroquinazoline-6-carboxylate (CAS 2773313-28-1)
Recommended Standards
- 2,2-Dichloro-1,1-bis(4-chlorophenyl)-2-fluoroethanol (CAS 1868-91-3)
- 4-Bromobenzene-1,3-disulfonyl dichloride (CAS 117122-41-5)
- 4,4'-(Hydrazine-1,2-diyl)bis(2,6-dichlorophenol) (CAS CATO-C4X-30363)
- 2,2-Dibromo-1,2-diphenylethan-1-one (CAS 15023-99-1)
- N-[2-(4-Bromo-2-fluorophenyl)ethyl]-N-methylamine (CAS 1216635-19-6)
- 4-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]piperidine hydrochloride (CAS 1181458-55-8)
- 4-(1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-yl)aniline (CAS 10179-54-1)
- 4-Chloro-6-(3-piperidinylmethoxy)pyrimidinehydrochloride (CAS 1185309-95-8)
- N-Propyl-3-(trifluoromethoxy)aniline (CAS 1020966-73-7)
- 6-Aminoquinolin-2-ol (CAS 79207-68-4)
- RMC6236 (CAS CATO-CIM-103914)
- 2-Carboxy-4,5-dimethoxyphenylboronic acid (CAS 1256345-91-1)
- Tert-butyl 6-((4-cyano-2-fluorobenzyl)oxy)-3',6'-dihydro-[2,4'-bipyridine]-1'(2'H)-carboxylate (CAS 2428642-40-2)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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