2-Chloro-6-naphthol CAS 40604-49-7
| CAS No. | 40604-49-7 |
| Molecular Formula | C10H7ClO |
| Molecular Weight | 178.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-6-naphthol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Chloro-6-naphthol (CAS 40604-49-7), a certified reference material (molecular formula C10H7ClO, MW 178.61 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-6-naphthol (C10H7ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7ClO |
| Molecular Weight | 178.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 1-Chloro-6-naphthol (CAS 116668-72-5)
- methyl 2-chloro-2-(oxolan-3-yl)acetate (CAS 1248819-31-9)
- 3-Chloro-2-hydroxypropyl methacrylate (CAS 13159-52-9)
- ethyl 5-chloro-4-oxopentanoate (CAS 14594-24-2)
- 1-Chloro-4-phenyl-3-butyn-2-one (CAS 176648-09-2)
- 1-Chloro-2-naphthol (CAS 633-99-8)
- 1-chloro-3-(1,4-dioxan-2-yl)propan-2-one (CAS 2573212-79-8)
- 1-Chloro-7-naphthol (CAS 29921-50-4)
Recommended Standards
- 2-Chloro-2-Fluoro-1-(2-Thienyl)Ethanone (CAS 58750-67-7)
- 2-Chloronaphthalen-1-ol (CAS 606-40-6)
- 2-Chloro-1H-indene-3-carbaldehyde (CAS 88099-28-9)
- 3-Chloro-1H-indene-2-carbaldehyde (CAS 74812-71-8)
- (2R,3S)-3-((tert-Butoxycarbonyl)amino)oxetane-2-carboxylic acid (CAS 2012574-97-7)
- BUtanoic acid, 2-ethyl-, (octahydro-4,7-methano-1H-indene-5,x-diyl)bis(methylene) ester (CAS 94277-23-3)
- 7-(Bromomethyl)-1,7-dimethylbicyclo[2.2.1]heptan-2-one (CAS 3751-96-0)
- cis-2-(4-Chlorobenzoyl)cyclopentane-1-carboxylic acid (CAS 733740-14-2)
- Methyl 2-(4-Methyl-3-indolyl)-2-oxoacetate (CAS 425640-05-7)
- Omeprazole Impurity 18 (CAS CATO-C4X-125518)
- 1-(3-Bromothiophen-2-yl)-N-((tetrahydrofuran-2-yl)methyl)methanamine (CAS 1250914-16-9)
- (2s,5s)-1-Benzyl-5-(methoxycarbonyl)pyrrolidine-2-carboxylic acid (CAS 111138-50-2)
- 4-Methyl-5-phenyl-1H-1,2,3-triazole (CAS 55324-06-6)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
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