2-Fluoro-4',5-dimethoxy-1,1'-biphenyl CAS 406482-29-9
| CAS No. | 406482-29-9 |
| Molecular Formula | C14H13FO2 |
| Molecular Weight | 232.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-4',5-dimethoxy-1,1'-biphenyl.
2-Fluoro-4',5-dimethoxy-1,1'-biphenyl (CAS 406482-29-9) is a high-purity analytical reference standard with the molecular formula C14H13FO2 and a molecular weight of 232.25 g/mol.
Structurally, 2-Fluoro-4',5-dimethoxy-1,1'-biphenyl (C14H13FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 232.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Fluoro-4',5-dimethoxy-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13FO2 |
| Molecular Weight | 232.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
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- ethyl 8-fluoro-1,4-dioxaspiro[4.5]decane-8-carboxylate (CAS 1260796-05-1)
- 4-Fluoro-2-(((pyridin-4-ylmethyl)amino)methyl)phenol (CAS 1269665-16-8)
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Recommended Standards
- 2-Benzyloxy-3-fluorobenzyl alcohol (CAS 628330-74-5)
- 2-Fluoro-4-methoxy-1-(phenylmethoxy)-benzene (CAS 540463-60-3)
- 2-(Benzyloxy)-4-fluoro-5-methylphenol (CAS 504414-10-2)
- 3-(4-Fluorophenyl)-1,4-diazaspiro[4.4]Non-3-en-2-one (CAS 899926-75-1)
- 5-Bromo-1-methyl-1H-imidazole-4-sulfonamide (CAS 89501-91-7)
- 5-(2-(2-Fluorophenyl)benzo[d]oxazol-5-yl)-1,3,4-oxadiazol-2-amine (CAS 1706441-72-6)
- 3-Bromo-2-(bromomethyl)-5-methylthiophene (CAS 857360-05-5)
- (2S,4R)-N,N-Dibenzyl-4-hydroxypyrrolidine-2-carboxamide (CAS 915205-76-4)
- 6-hydroxy-1,5-naphthyridine-3-carboxylic acid (CAS 1508822-90-9)
- 2-Amino-N-cyclopropyl-N-(isoquinolin-1-ylmethyl)acetamide (CAS 1353980-31-0)
- 2,2-Dimethylchromane-6-carbonitrile (CAS 132685-98-4)
- 5-Ethyl-4-(2-fluorophenyl)-1h-pyrazol-3-amine (CAS 1309887-58-8)
- 1-(1-Bromo-2,2,2-trifluoro-ethyl)-2-chloro-benzene (CAS 1349715-54-3)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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