(S)-3-(trimethylsilyl)pyrrolidin-2-one CAS 406497-08-3
| CAS No. | 406497-08-3 |
| Molecular Formula | C7H15NOSi |
| Molecular Weight | 157.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 157.29 g/mol gives (S)-3-(trimethylsilyl)pyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(S)-3-(trimethylsilyl)pyrrolidin-2-one (CAS 406497-08-3) is a high-purity analytical reference standard with the molecular formula C7H15NOSi and a molecular weight of 157.29 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, (S)-3-(trimethylsilyl)pyrrolidin-2-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 157.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H15NOSi |
| Molecular Weight | 157.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related S Standards
- N-Trimethylsilyl-2-pyrrolidone (CAS 14468-90-7)
- 2-Methyl-2-[(trimethylsilyl)oxy]propanenitrile (CAS 18296-11-2)
- 2-Trimethylsilyl thiazole (CAS 79265-30-8)
- 5-(Trimethylsilyl)thiazole (CAS 79265-36-4)
- (E)-(3-(Trimethylsilyl)allyl)boronic acid (CAS 774597-15-8)
- 2-(Trimethylsilyl)thiophene (CAS 18245-28-8)
- (Trimethylsilyl)methacrylate (CAS 13688-56-7)
- (Trimethylsilyl)methyl acrylate (CAS 67186-35-0)
Recommended Standards
- Amantadine-d6 (CAS 1219805-53-4)
- pentan-2-yl(pentyl)amine (CAS 1019518-65-0)
- 4-(Methoxydimethylsilyl)butanenitrile (CAS 143203-47-8)
- n-Butyl-3-methylpentan-2-amine (CAS 1042535-90-9)
- [(2-Chloro-6-fluorophenyl)methyl](prop-2-en-1-yl)amine (CAS 62924-63-4)
- [(1,1-dioxo-1λ6-thiolan-3-yl)methyl]urea (CAS 55260-96-3)
- 4-(3-amino-1,2-benzoxazol-7-yl)-2-thiazol-2-yl-but-3-yn-2-ol (CAS 2539836-89-8)
- 2-Chlorobenzyl (E)-(2-(furan-2-yl)vinyl)carbamate (CAS 338399-83-0)
- (Chloro-difluoro-methyl)-trimethyl-silane (CAS 115262-00-5)
- Methyl (2S,3S)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylate (CAS 1509941-50-7)
- 1-Bromo-2,6-dimethylheptane (CAS 51979-43-2)
- 2-((4,6-Dimethylpyrimidin-2-yl)thio)-N-(p-tolyl)acetamide (CAS 202805-41-2)
- Isavuconazole Impurity 100 Iodization HCl (CAS CATO-C4X-1236100)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com