(2,3-Difluorophenyl)(4-methylpiperazin-1-yl)methanone CAS 406918-24-9
| CAS No. | 406918-24-9 |
| Molecular Formula | C12H14F2N2O |
| Molecular Weight | 240.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2,3-Difluorophenyl)(4-methylpiperazin-1-yl)methanone (CAS 406918-24-9), molecular formula C12H14F2N2O and molecular weight 240.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2,3-Difluorophenyl)(4-methylpiperazin-1-yl)methanone (C12H14F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14F2N2O |
| Molecular Weight | 240.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 1-(2,4-Difluorophenyl)-2-(piperazin-1-yl)ethan-1-one (CAS 1072876-84-6)
- N-(3,5-Difluorophenyl)piperidine-2-carboxamide (CAS 1078791-29-3)
- 1-(2,4-Difluorophenyl)cyclohexane-1-carboxylic acid (CAS 1260804-27-0)
- 1-(3,5-Difluorophenyl)-cyclohexanecarboxylic acid (CAS 1260804-37-2)
- 1-(3,5-Difluorophenyl)-3,3-dimethylcyclobutane-1-carboxylic acid (CAS 1468625-03-7)
- N-(2,4-difluorophenyl)piperidine-2-carboxamide (CAS 193342-38-0)
- (2,4-difluorophenyl)(piperidin-4-yl)methanone oxime (CAS 84163-46-2)
- 5-(2,6-Difluorophenyl)thiophene-2-carboxylic acid (CAS 1094440-66-0)
Recommended Standards
- (1S)-1-((4S,5S)-5-Hydroxy-2-phenyl-1,3-dioxan-4-yl)ethane-1,2-diol (CAS 53131-06-9)
- (2R,3R,4R)-5-(benzyloxy)-2,3,4-trihydroxypentanal (CAS 72369-89-2)
- (1R,4aS,7aS)-Methyl 7-(hydroxymethyl)-1-methoxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (CAS 69977-52-2)
- (2R,3S,4R,5R)-2-(Benzyloxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 5329-50-0)
- 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carbonitrile (CAS 1630906-47-6)
- 2-Methyl-4-phenylimidazole (CAS 13739-48-5)
- 4-Amino-6-(difluoromethyl)-3-methoxypicolinaldehyde (CAS 1805220-36-3)
- Rac-(1S,2S,3R)-3-amino-1,2-cyclopentanediol hydrochloride (CAS 98672-77-6)
- Bis(acetylacetonato)dimethylstannane (CAS 16925-15-8)
- Ethyl 2-chloro-2-ethoxyacetate (CAS 34006-60-5)
- [1,4]Dioxan-2-ylmethyl-methyl-amine hydrochloride (CAS 918621-33-7)
- 2-((5-(3-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3,5-dichlorophenyl)acetamide (CAS 336174-73-3)
- 3-Indolyl-Acetonitrile (CAS 771-51-7)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
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