2,2,2-trifluoro-N-(2,2,2-trifluoroethyl)acetamide CAS 407-37-4
| CAS No. | 407-37-4 |
| Molecular Formula | C4H3F6NO |
| Molecular Weight | 195.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,2,2-trifluoro-N-(2,2,2-trifluoroethyl)acetamide (CAS 407-37-4), a certified reference material (molecular formula C4H3F6NO, MW 195.06 g/mol) for analytical method development and quality control.
The molecular framework of 2,2,2-trifluoro-N-(2,2,2-trifluoroethyl)acetamide (C4H3F6NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H3F6NO |
| Molecular Weight | 195.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trifluoro Standards
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- 2,2,2-Trifluoro-1-(3-fluoropyridin-2-yl)ethan-1-ol (CAS 2092020-54-5)
- 2,2,2-Trifluoro-1-(6-fluoropyridin-3-yl)ethan-1-ol (CAS 950687-46-4)
- 4,4,4-Trifluoro-3-trifluoromethylbutylamine (CAS 954238-58-5)
- 2,2,2-Trifluoro-N-(3-hydroxybicyclo[1.1.1]Pentan-1-yl)acetamide (CAS 1628196-27-9)
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