6,8-Dichloro-2-(4-methylphenyl)-4H-3,1-benzoxazin-4-one CAS 40728-71-0
| CAS No. | 40728-71-0 |
| Molecular Formula | C15H9Cl2NO2 |
| Molecular Weight | 306.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6,8-Dichloro-2-(4-methylphenyl)-4H-3,1-benzoxazin-4-one (C15H9Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6,8-Dichloro-2-(4-methylphenyl)-4H-3,1-benzoxazin-4-one (CAS 40728-71-0) is a high-purity analytical reference standard with the molecular formula C15H9Cl2NO2 and a molecular weight of 306.14 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6,8-Dichloro-2-(4-methylphenyl)-4H-3,1-benzoxazin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H9Cl2NO2 |
| Molecular Weight | 306.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- N-(3-(1H-Pyrrolo[2,3-b]pyridin-1-yl)propyl)butane-1-sulfonamide (CAS 1798023-99-0)
- 4-[(Tetrahydro-2-furanyl)methoxy]benzonitrile (CAS 1017033-37-2)
- 1-(6-Fluoropyridin-2-yl)cyclopropan-1-amine hydrochloride (CAS 2149601-88-5)
- 1-Chloro-3-(1-phenylvinyl)benzene (CAS 29265-81-4)
- 4-(3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl)-2-phenylphthalazin-1(2H)-one (CAS 1291847-05-6)
- 6-(2,5-Difluorophenyl)picolinaldehyde (CAS 887979-77-3)
- 3-(2-(2,4,6-Trichlorophenyl)hydrazono)indolin-2-one (CAS 298207-63-3)
- 4-Iodo-2-(trifluoromethoxy)benzonitrile (CAS 1807054-38-1)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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