6-Amino-5-methylpyridine-3-sulfonic acid CAS 40741-48-8
| CAS No. | 40741-48-8 |
| Molecular Formula | C6H8N2O3S |
| Molecular Weight | 188.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-5-methylpyridine-3-sulfonic acid.
6-Amino-5-methylpyridine-3-sulfonic acid (CAS 40741-48-8) is a high-purity analytical reference standard with the molecular formula C6H8N2O3S and a molecular weight of 188.20 g/mol.
6-Amino-5-methylpyridine-3-sulfonic acid (C6H8N2O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O3S |
| Molecular Weight | 188.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-6-hydroxybenzenesulfonamide (CAS 1243393-32-9)
- 2-Amino-5,6-dihydro-4-oxo-4H-1,3-thiazine-5-acetic acid (CAS 137017-77-7)
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Recommended Standards
- 6-Amino-4-methylpyridine-3-sulfonic acid (CAS 691383-27-4)
- 6-Fluoro-[1,1'-biphenyl]-3-ol (CAS 209474-37-3)
- 6-(Ethylsulfonyl)pyridazin-3(2H)-one (CAS 62645-16-3)
- 6-fluoro-1-benzofuran-2-carboxylic acid (CAS 26018-66-6)
- 2-(4-Bromothiophen-2-yl)oxirane (CAS 1485632-69-6)
- n-(2,6-Dimethoxybenzyl)butan-1-amine (CAS 1179082-36-0)
- Benzyl (2-hydroxyethyl)(propyl)carbamate (CAS 371197-74-9)
- 2-(4-Fluorobenzylidene)-1h-indene-1,3(2h)-dione (CAS 16210-64-3)
- 5-Isocyanato-1-methyl-1H-imidazole (CAS 499770-99-9)
- Methyl (R)-2-(((benzyloxy)carbonyl)amino)-3-(bicyclo[1.1.1]pentan-1-yl)propanoate (CAS 2322929-20-2)
- N-(1-(o-tolyl)ethyl)propionamide (CAS 1341300-62-6)
- 1-Ethyl-3-phenylpiperazine-2,5-dione (CAS 1214164-70-1)
- Clopidogrel Impurity 79 (CAS CATO-C4X-102979)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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