Ethyl 5-(hydroxymethyl)-1-phenyl-1H-pyrazole-3-carboxylate CAS 40753-66-0
| CAS No. | 40753-66-0 |
| Molecular Formula | C13H14N2O3 |
| Molecular Weight | 246.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Ethyl 5-(hydroxymethyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 40753-66-0), a certified reference material (molecular formula C13H14N2O3, MW 246.26 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 5-(hydroxymethyl)-1-phenyl-1H-pyrazole-3-carboxylate (C13H14N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O3 |
| Molecular Weight | 246.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 2-(Hydroxymethyl)-5-((2-methylbenzyl)oxy)-4h-pyran-4-one (CAS 1216140-45-2)
- Methyl 1-[2-(hydroxymethyl)phenyl]-5-methyl-1H-pyrazole-3-carboxylate (CAS 1251950-60-3)
- (5-(Hydroxymethyl)-1-methyl-1H-pyrazol-3-yl)methyl benzoate (CAS 2450997-89-2)
- 1-(Hydroxymethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid (CAS 73198-02-4)
- 2-(Hydroxymethyl)-5-((4-methylbenzyl)oxy)-4H-pyran-4-one (CAS 865658-82-8)
- 3-(Hydroxymethyl)phenethyl furan-3-carboxylate (CAS 61761-78-2)
- 2-(Hydroxymethyl)naphtho[1,2-b]thiophene 1,1-dioxide (CAS 931114-41-9)
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Recommended Standards
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- 2-Amino-4-(2-fluorophenyl)butanoic acid (CAS 225233-81-8)
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