Methyl 2-(5-Methyl-3-indolyl)-2-oxoacetate CAS 408356-28-5
| CAS No. | 408356-28-5 |
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.22 g/mol gives Methyl 2-(5-Methyl-3-indolyl)-2-oxoacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 2-(5-Methyl-3-indolyl)-2-oxoacetate (CAS 408356-28-5), molecular formula C12H11NO3 and molecular weight 217.22 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 2-(5-Methyl-3-indolyl)-2-oxoacetate (C12H11NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3 |
| Molecular Weight | 217.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl 2-(4-oxoquinolin-1(4H)-yl)acetate (CAS 91538-63-5)
- Methyl 2-(6-Methyl-3-indolyl)-2-oxoacetate (CAS 408356-30-9)
- Methyl 2-(4-Methyl-3-indolyl)-2-oxoacetate (CAS 425640-05-7)
- Methyl 2-(7-Methyl-3-indolyl)-2-oxoacetate (CAS 425640-13-7)
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