(R,R)-Formoterol Impurity 57 CAS 408497-91-6
| CAS No. | 408497-91-6 |
| Molecular Formula | C26H30N2O4 |
| Molecular Weight | 434.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
(R,R)-Formoterol Impurity 57 (CAS 408497-91-6) is a certified pharmaceutical impurity reference standard with the molecular formula C26H30N2O4 and a molecular weight of 434.53 g/mol.
The molecular framework of (R,R)-Formoterol Impurity 57 (C26H30N2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures (R,R)-Formoterol Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H30N2O4 |
| Molecular Weight | 434.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Recommended Standards
- Ondansetron Impurity 12 (CAS 1365727-09-8)
- Formoterol EP Impurity H (Enantiomer Mixture) (CAS CATO-C4X-15258)
- Terbutaline Impurity 83 (CAS CATO-C4X-118383)
- (R,R)-Formoterol EP Impurity H (CAS 1337876-26-2)
- Norepinephrine Impurity 42 (CAS 28822-73-3)
- Relugolix Impurity 5 (CAS CATO-C4X-24295)
- Warfarin sodium EP Impurity A (CAS 15156-56-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com