3-Amino-5-chloropyridine-2-carbonitrile CAS 408538-29-4
| CAS No. | 408538-29-4 |
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Amino-5-chloropyridine-2-carbonitrile.
CATO supplies 3-Amino-5-chloropyridine-2-carbonitrile (CAS 408538-29-4), a certified reference material (molecular formula C6H4ClN3, MW 153.57 g/mol) for analytical method development and quality control.
3-Amino-5-chloropyridine-2-carbonitrile (C6H4ClN3) contains a nitrile group, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3 |
| Molecular Weight | 153.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 4-Amino-6-chloropicolinonitrile (CAS 1206249-10-6)
- 5-Amino-6-chloronicotinonitrile (CAS 1260672-23-8)
- 6-Amino-3-chloropicolinonitrile (CAS 1314976-40-3)
- 5-Amino-2-chloroisonicotinonitrile (CAS 1359828-87-7)
- 2-amino-5-chloro-pyridine-4-carbonitrile (CAS 1393106-21-2)
- 2-Amino-3-chloroisonicotinonitrile (CAS 1393106-23-4)
- 5-Amino-6-chloropicolinonitrile (CAS 1402834-69-8)
- 6-Amino-5-chloronicotinonitrile (CAS 156361-02-3)
Recommended Standards
- 3-Amino-5-chloroisonicotinonitrile (CAS 211571-70-9)
- 3-Amino-6-chloropyridine-2-carbonitrile (CAS 95095-84-4)
- 3-Amino-2-chloroisonicotinonitrile (CAS 342899-37-0)
- 3-Chloro-4-hydroxybenzonitrile (CAS 2315-81-3)
- 173458-82-7 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5,6-diphenyl-7-(phenylmethyl)- CTK0A7674 (CAS 173458-82-7)
- 5-Bromo-N-(pyridin-3-ylmethyl)pyridin-2(1h)-imine (CAS 1036505-24-4)
- 1-Cyclohexylpentan-1-ol (CAS 7338-43-4)
- 4-[(4-methoxyphenyl)methylidene]-1,2,3,4-tetrahydroacridine-9-carboxylic acid (CAS 380342-08-5)
- N'1-(2-chloroacetyl)-2-{5-[3,5-di(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazol-2-yl}propanohydrazide (CAS 680214-90-8)
- N-((2-(tert-butylthio)ethyl)carbamoyl)-4-methylbenzenesulfonamide (CAS 866008-88-0)
- tert-Butyl (((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)methyl)carbamate (CAS 1401666-58-7)
- (E)-4-ethoxy-4-cyclohexylamino-1,1,1-trifluorobut-3-en-2-one (CAS 869946-57-6)
- 2-(Trifluoromethyl)benzenesulfonyl fluoride (CAS 52201-00-0)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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