1-(4-Fluorophenyl)-4-iodo-1-butanone CAS 40862-32-6

Purity 97%+In StockPharmaceutical Standards
CAS No.40862-32-6
Molecular FormulaC10H10FIO
Molecular Weight292.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Fluorophenyl)-4-iodo-1-butanone CAS 40862-32-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 292.09 g/mol gives 1-(4-Fluorophenyl)-4-iodo-1-butanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(4-Fluorophenyl)-4-iodo-1-butanone (CAS 40862-32-6) is a high-purity analytical reference standard with the molecular formula C10H10FIO and a molecular weight of 292.09 g/mol.

The molecular framework of 1-(4-Fluorophenyl)-4-iodo-1-butanone (C10H10FIO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Fluorophenyl)-4-iodo-1-butanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H10FIO
Molecular Weight292.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1968
Halogen ContentF/I-containing

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