1,2,3-Thiadiazole-4-carbonitrile CAS 4100-24-7
| CAS No. | 4100-24-7 |
| Molecular Formula | C3HN3S |
| Molecular Weight | 111.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,2,3-Thiadiazole-4-carbonitrile (CAS 4100-24-7) is a high-purity analytical reference standard with the molecular formula C3HN3S and a molecular weight of 111.13 g/mol.
The molecular framework of 1,2,3-Thiadiazole-4-carbonitrile (C3HN3S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1,2,3-Thiadiazole-4-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3HN3S |
| Molecular Weight | 111.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiadiazole Standards
- 1,3,4-Thiadiazole-2-carbonitrile (CAS 1121585-02-1)
- 1,2,3-Thiadiazole-5-carbaldehyde (CAS 10200-61-0)
- 1,2,3-Thiadiazole-4-carbaldehyde (CAS 27643-15-8)
- 1,2,5-Thiadiazole-3-carbaldehyde (CAS 75238-60-7)
- 1,2,4-thiadiazole-3,5-diamine (CAS 34283-30-2)
- 1,2,5-Thiadiazole-3,4-diamine (CAS 55904-36-4)
- 1,3,4-Thiadiazole-2,5-diamine (CAS 2937-81-7)
- 1,2,5-Thiadiazole 1,1-dioxide (CAS 140651-41-8)
Recommended Standards
- 3-Pyridinecarboxaldehyde-d (CAS 258854-80-7)
- Paliperidone Impurity 28 (CAS 55665-95-7)
- 4-Isocyanotetrahydro-2H-pyran (CAS 1000699-00-2)
- Ezetimibe Impurity 56 (CAS 371-40-4)
- 5,6,7,8-Tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine (CAS 86029-68-7)
- (3,5-Dimethyl-1-phenyl-1h-pyrazol-4-yl)methanamine (CAS 400877-11-4)
- Benzyl (4-mercaptocyclohexyl)carbamate (CAS 1353983-26-2)
- Tert-butyl 5-oxohexahydrocyclopenta[b]pyrrole-1(2H)-carboxylate (CAS 1507246-53-8)
- Tert-butyl 2-(1-amino-2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate (CAS 1334490-49-1)
- (S)-1-(4-(difluoromethyl)-3-fluorophenyl)-2-methylpropan-1-amine (CAS 1212940-91-4)
- 7-Methoxy-2-(trifluoromethyl)-1H-indole (CAS 1780292-99-0)
- 5-cyano-1H-indole-2-carboxylic acid (CAS 169463-44-9)
- n-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((furan-2-ylmethyl)amino)acetamide hydrochloride (CAS 1171599-63-5)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com