3-Acetyl-8-chloro-2-phenylquinolin-4(1H)-one CAS 412336-76-6
| CAS No. | 412336-76-6 |
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.74 g/mol gives 3-Acetyl-8-chloro-2-phenylquinolin-4(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Acetyl-8-chloro-2-phenylquinolin-4(1H)-one (CAS 412336-76-6) is a high-purity analytical reference standard with the molecular formula C17H12ClNO2 and a molecular weight of 297.74 g/mol.
Structurally, 3-Acetyl-8-chloro-2-phenylquinolin-4(1H)-one (C17H12ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 297.74 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Acetyl-8-chloro-2-phenylquinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Acetyl Standards
- 11-Chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one, 97% (CAS 1012884-46-6)
- 3-Benzyl-4-chloro-1-phenyl-1h-pyrrole-2,5-dione (CAS 1033200-81-5)
- 6-Chloro-2-(p-tolyl)quinoline-4-carboxylic acid, 97% (CAS 103914-61-0)
- 2-(2-Chloro-6-morpholino-7H-purin-8-yl)propan-2-ol (CAS 1198171-62-8)
- 6-Chloro-3-methyl-2-phenylquinoline-4-carboxylic acid (CAS 154869-06-4)
- 2-(2-Chloro-4-phenylquinolin-3-yl)acetic acid (CAS 1706450-09-0)
- 6-Chloro-N2,N4-diphenyl-1,3,5-triazine-2,4-diamine (CAS 1973-09-7)
- 2-Chloro-3-(m-tolylamino)naphthalene-1,4-dione (CAS 64505-54-0)
Recommended Standards
- 3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one (CAS 58375-08-9)
- 4-(2-Chlorophenyl)-3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazin-2-amine (CAS 78650-07-4)
- 3-(6-Chloropyridazin-3-yl)-1-cyclopropanecarbonyl-1H-indole (CAS 439093-74-0)
- 4-(3-Chloro-4-methylbenzylidene)-2-phenyloxazol-5(4H)-one (CAS 61887-36-3)
- 5-Bromo-2,4-dimethylbenzoic acid (CAS 842136-27-0)
- 6-Chloro-2-methyl-5-nitro-3,4'-bipyridine (CAS 1214377-62-4)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-1,2-dihydropyrimidin-2-one (CAS 338420-38-5)
- Methyl 5-amino-4-(6-methyl-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-2-((methylsulfonyl)methyl)benzoate (CAS 2313230-44-1)
- Lansoprazole Impurity 10 (CAS 1083100-27-9)
- 2,2,2-Trifluoro-1-(5-fluoro-2-(pentyloxy)phenyl)ethan-1-one (CAS 1443313-49-2)
- 2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinamide (CAS 1214365-98-6)
- 2-Ethoxy-6-methylpyridine-3-carboxylic acid (CAS 933696-84-5)
- (S)-tert-Butyl ((1-(2-aminoacetyl)pyrrolidin-2-yl)methyl)(ethyl)carbamate (CAS 1354018-99-7)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com