8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride CAS 41266-63-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride.

8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride (CAS 41266-63-1) is a high-purity analytical reference standard with the molecular formula C11H11FN2HCl and a molecular weight of 226.68 g/mol.

8-fluoro-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride (C11H11FN2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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