Methyl 4-chloro-5-methoxybenzo[b]thiophene-2-carboxylate CAS 41280-83-5
| CAS No. | 41280-83-5 |
| Molecular Formula | C11H9ClO3S |
| Molecular Weight | 256.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Methyl 4-chloro-5-methoxybenzo[b]thiophene-2-carboxylate (CAS 41280-83-5), a certified reference material (molecular formula C11H9ClO3S, MW 256.71 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 4-chloro-5-methoxybenzo[b]thiophene-2-carboxylate (C11H9ClO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl 4-chloro-5-methoxybenzo[b]thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9ClO3S |
| Molecular Weight | 256.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Ethyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate (CAS 101667-98-5)
- N-(6-chloro-1,3-benzothiazol-2-yl)-n-methylglycine (CAS 104344-50-5)
- Methyl 5-chloro-4-(1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxylate (CAS 1047630-52-3)
- 4-Chloro-2-methylquinoline-8-sulfonamide (CAS 1121527-72-7)
- Ethyl 4-chloro-2-methylthieno[2,3-d]pyrimidine-5-carboxylate (CAS 1215910-73-8)
- 5-Chloro-3-(3,4-dimethoxyphenyl)-1,2,4-thiadiazole (CAS 1221346-01-5)
- N-(4-Chloro-1,3-benzothiazol-2-yl)-N-methylglycine (CAS 1353000-10-8)
- 5-Chloro-3-(2,3-dimethoxyphenyl)-1,2,4-thiadiazole (CAS 1378261-24-5)
Recommended Standards
- methyl 4-chloro-2,5-dimethylthieno[2,3-d]pyrimidine-6-carboxylate (CAS 872319-75-0)
- Samarium(III) chloride (CAS 10361-82-7)
- Methyl 3-chloro-5-methoxybenzo[b]thiophene-2-carboxylate (CAS 41280-81-3)
- (3-Chloro-4-fluorophenyl)(5-methylthiophen-2-yl)methanol (CAS 1443312-20-6)
- (3-Chlorobenzo[b]thiophen-2-yl)(4-(4-fluorophenyl)piperazin-1-yl)methanone (CAS 351329-77-6)
- 5-Fluoro-N-(4-fluorobenzyl)-2-methylaniline (CAS 1019514-90-9)
- 2-(Trifluoromethyl)-3h-imidazo[4,5-b]pyridine (CAS 13797-63-2)
- Prostaglandin E1 sodium (CAS 27930-45-6)
- 1-(4-Methanesulfonyl-phenyl)-2-phenyl-ethane-1,2-dione (CAS 54945-18-5)
- 4-Cyclopropoxy-3-isopropoxypicolinaldehyde (CAS 1243403-55-5)
- N-(4-Chloro-2-methyl-3-(trifluoromethyl)phenyl)pivalamide (CAS 112641-23-3)
- N-(5-cyano-2-(methylthio)phenyl)benzamide (CAS 303147-46-8)
- 2-(Furan-3-yl)pyrrolidine-1-carbaldehyde (CAS 1355177-56-8)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com