2-Bromo-4-(4-fluorophenyl)-1,3-thiazole CAS 412923-44-5
| CAS No. | 412923-44-5 |
| Molecular Formula | C9H5BrFNS |
| Molecular Weight | 258.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole.
2-Bromo-4-(4-fluorophenyl)-1,3-thiazole (CAS 412923-44-5) is a high-purity analytical reference standard with the molecular formula C9H5BrFNS and a molecular weight of 258.11 g/mol.
Structurally, 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole (C9H5BrFNS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 258.11 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4-(4-fluorophenyl)-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrFNS |
| Molecular Weight | 258.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- N-(6-Chloro-3-iodopyridin-2-yl)pivalamide (CAS 800402-05-5)
- 2-Chloro-n,6-dimethyl-n-phenylpyrimidin-4-amine (CAS 93669-49-9)
- Urolignoside (CAS 131723-83-6)
- 3-((5-(p-Tolyl)thieno[2,3-d]pyrimidin-4-yl)thio)propanoic acid (CAS 329907-28-0)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
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