2-((Trimethylsilyl)oxy)pyrimidin-4-amine CAS 41381-21-9

Purity 97%+In StockPharmaceutical Standards
CAS No.41381-21-9
Molecular FormulaC7H13N3OSi
Molecular Weight183.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((Trimethylsilyl)oxy)pyrimidin-4-amine CAS 41381-21-9 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-((Trimethylsilyl)oxy)pyrimidin-4-amine (CAS 41381-21-9) is a high-purity analytical reference standard with the molecular formula C7H13N3OSi and a molecular weight of 183.28 g/mol.

The molecular framework of 2-((Trimethylsilyl)oxy)pyrimidin-4-amine (C7H13N3OSi) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H13N3OSi
Molecular Weight183.28 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1968
Nitrogen Atoms3

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