α-Phenyl-α-(trifluoromethyl)-1H-pyrrole-2-methanol CAS 4156-00-7
| CAS No. | 4156-00-7 |
| Molecular Formula | C12H10F3NO |
| Molecular Weight | 241.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
α-Phenyl-α-(trifluoromethyl)-1H-pyrrole-2-methanol (CAS 4156-00-7), molecular formula C12H10F3NO and molecular weight 241.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of α-Phenyl-α-(trifluoromethyl)-1H-pyrrole-2-methanol (C12H10F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), α-Phenyl-α-(trifluoromethyl)-1H-pyrrole-2-methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3NO |
| Molecular Weight | 241.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Phenyl Standards
- 1-(3-(Trifluoromethyl)benzyl)-1H-pyrazol-4-amine (CAS 1002033-51-3)
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- (4-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)phenyl)methanamine (CAS 1006951-06-9)
- 1-(2-(Trifluoromethyl)benzyl)-1H-pyrazol-5-amine (CAS 1015846-00-0)
- 1-(3-(Trifluoromethyl)benzyl)-1h-pyrazol-5-amine (CAS 1052563-64-0)
- 1-(4-(Trifluoromethyl)benzyl)-1H-pyrazol-4-amine (CAS 1104806-98-5)
- (5-(4-(Trifluoromethyl)phenyl)furan-2-yl)methanamine (CAS 1152622-44-0)
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Recommended Standards
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- tert-Butyl 3-hydroxy-3-(trifluoromethyl)azetidine-1-carboxylate (CAS 398489-42-4)
- Nilotinib Impurity 24 (CAS 641571-16-6)
- 5,5-Dimethyl-2-(4-propylphenyl)-1,3,2-dioxaborinane (CAS 574755-16-1)
- 3-[(4-Methylphenyl)methyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione (CAS 1223883-16-6)
- 2-[4-(4-Nitrophenyl)piperazino]ethyl 3-chlorobenzenecarboxylate (CAS 338748-60-0)
- 2-(Carboxymethyl)-4,5-dimethoxybenzoic acid, >96% (CAS 3809-00-5)
- Methyl 5-chloro-2-[(dimethylsulfamoyl)oxy]benzoate (CAS 338406-00-1)
- 1-(1-Propyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-2-yl)methyl)methanamine hydrochloride (CAS 1856063-76-7)
- Tert-butyl 4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)piperidine-1-carboxylate (CAS 1417794-57-0)
- Difenoconazole (CAS 119446-68-3)
- 4-Chloro-N'-(6-chloropyridin-2-yl)-N'-methylbenzohydrazide (CAS 400085-77-0)
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