8-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS 41565-83-7
| CAS No. | 41565-83-7 |
| Molecular Formula | C10H13N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride.
8-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 41565-83-7), molecular formula C10H13NHCl and molecular weight 183.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 8-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13N HCl |
| Molecular Weight | 183.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 1-Methyl-5-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazole-4-carboxylic acid (CAS 1006455-90-8)
- 1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid (CAS 101301-17-1)
- 7-Ethyl-1,2,3,4-tetrahydroisoquinoline (CAS 1017125-75-5)
- 2-[(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)amino]acetic acid (CAS 1018299-34-7)
- 5,6,7,8-Tetrahydroisoquinoline-4-carboxylic acid (CAS 1019111-31-9)
- 3-(1,2,3,4-Tetrahydroisoquinoline-2-carbonyl)phenol (CAS 1019438-49-3)
- 2-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1022919-86-3)
- Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate (CAS 1028330-54-2)
Recommended Standards
- 3,3'-Diethoxy-[1,1'-biphenyl]-4,4'-dicarboxylicacid (CAS 2051918-30-8)
- 2,3-Dichloro-4-methylbenzonitrile (CAS 1804896-39-6)
- 5-(Quinolin-6-yl)-1H-pyrazol-3-amine (CAS 1040724-21-7)
- 1-(2-Bromopyridin-4-yl)cyclopropan-1-amine (CAS 1060811-37-1)
- Ethyl 3-(3-chloro-2-fluorophenoxy)propanoate (CAS 1443338-61-1)
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- 2,7-Di(pyridin-4-yl)-9H-carbazole (CAS 2768518-72-3)
- (1-(Bromomethyl)cyclopropyl)methanol (CAS 81469-27-4)
- 8-(5-Chloro-1-(2,4-dichlorophenyl)-6-oxo-1,6-dihydropyridazin-4-yl)-2-phenyl-1,2,4,8-tetraazaspiro[4.5]Decan-3-one (CAS 338413-92-6)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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