3-(4-Fluorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acrylonitrile CAS 415688-14-1
| CAS No. | 415688-14-1 |
| Molecular Formula | C18H10F2N2S |
| Molecular Weight | 324.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Fluorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acrylonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(4-Fluorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acrylonitrile (CAS 415688-14-1) is a high-purity analytical reference standard with the molecular formula C18H10F2N2S and a molecular weight of 324.35 g/mol.
The molecular framework of 3-(4-Fluorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acrylonitrile (C18H10F2N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Fluorophenyl)-2-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acrylonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10F2N2S |
| Molecular Weight | 324.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-Bromo-1-(cyclobutylmethyl)-1H-pyrazole (CAS 1216096-92-2)
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- 2-(5-(((4-Chlorophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)acetic acid (CAS 1087648-35-8)
- 5-(1-acetamidoethyl)thiophene-2-sulfonyl chloride (CAS 1016749-39-5)
- 3-(5-Fluoropyridin-2-yl)thiazolidine (CAS 1707358-04-0)
- 2,2,2-Trifluoro-1-(3-fluoropyridin-2-yl)ethan-1-ol (CAS 2092020-54-5)
- tert-Butyl (3-chloro-4-formylphenyl)carbamate (CAS 1210727-96-0)
- (2-(tert-Butoxy)-4-cyclopropoxyphenyl)methanamine (CAS 1243459-94-0)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
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