1-(Chloromethyl)-4-(difluoromethoxy)benzene CAS 41772-09-2
| CAS No. | 41772-09-2 |
| Molecular Formula | C8H7ClF2O |
| Molecular Weight | 192.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Chloromethyl)-4-(difluoromethoxy)benzene (CAS 41772-09-2) is a high-purity analytical reference standard with the molecular formula C8H7ClF2O and a molecular weight of 192.59 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-(Chloromethyl)-4-(difluoromethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(Chloromethyl)-4-(difluoromethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClF2O |
| Molecular Weight | 192.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-1,3-difluoro-5-methoxybenzene (CAS 1183153-32-3)
- 1-(Chloromethyl)-2,5-difluoro-4-methoxybenzene (CAS 1261645-61-7)
- 5-(chloromethyl)-1,3-difluoro-2-methoxybenzene (CAS 1507562-26-6)
- 4-(Chloromethyl)-5-(difluoromethyl)pyridin-2-amine (CAS 1805195-09-8)
- 6-(Chloromethyl)-3-(difluoromethyl)pyridin-2-amine (CAS 1806008-95-6)
- 6-(Chloromethyl)-4-(difluoromethyl)pyridin-2-amine (CAS 1806774-49-1)
- 1-(Chloromethyl)-2-(difluoromethoxy)benzene (CAS 42145-50-6)
- 1-(Chloromethyl)-3-(difluoromethoxy)benzene (CAS 42145-45-9)
Recommended Standards
- 1-Chloro-2,4-difluoro-5-(methoxymethyl)benzene (CAS 2379322-04-8)
- 1-Chloro-3-(difluoromethoxy)-2-methylbenzene (CAS 960249-91-6)
- (S)-2-Chloro-1-(2,4-difluorophenyl)ethan-1-ol (CAS 330156-49-5)
- 1-Chloro-3-(difluoromethyl)-2-methoxybenzene (CAS 943830-41-9)
- 2-Bromo-1-(2,4-dimethylphenyl)ethan-1-one (CAS 26346-85-0)
- Benzyl (4-amino-1-(cyanomethyl)cyclohexyl)carbamate (CAS 1656989-86-4)
- 2-Amino-4-phenylthiophene-3-carboxamide (CAS 150302-19-5)
- 1-(6-Bromopyridin-2-yl)-2,2,2-trifluoroethan-1-amine (CAS 886364-60-9)
- 1-(2,6-Difluorobenzyl)urea (CAS 17751-24-5)
- 4-Amino-N-(4-fluorophenyl)benzenesulfonamide hydrochloride (CAS 1048640-18-1)
- 5-Methyl-2-(2-naphthyloxy)aniline (CAS 946683-17-6)
- tert-butyl 3-(fluoromethyl)-3-hydroxy-piperidine-1-carboxylate (CAS 1415841-81-4)
- N-(2-Bromo-5-iodopyridin-3-yl)pivalamide (CAS 1203498-93-4)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com