2-chloro-6-methoxy-4-nitroaniline CAS 41956-18-7
| CAS No. | 41956-18-7 |
| Molecular Formula | C7H7ClN2O3 |
| Molecular Weight | 202.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-chloro-6-methoxy-4-nitroaniline (CAS 41956-18-7) is a high-purity analytical reference standard with the molecular formula C7H7ClN2O3 and a molecular weight of 202.60 g/mol.
The molecular framework of 2-chloro-6-methoxy-4-nitroaniline (C7H7ClN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O3 |
| Molecular Weight | 202.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Chloro-6-methoxy-4-methyl-3-nitropyridine (CAS 2387444-27-9)
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- 3-Chloro-5-methoxy-2-nitroaniline (CAS 2091591-51-2)
- 2-Chloro-6-iodopyridine (CAS 258506-66-0)
- Ethyl 4-hydroxytetrahydrofuran-2-carboxylate (CAS 1333319-61-1)
- tert-Butyl (4-bromo-3-chlorophenyl)carbamate (CAS 1092493-67-8)
- 5-Fluoro-2-methyl-3-nitrophenol (CAS 1803792-34-8)
- AG-041R (CAS 199800-49-2)
- 22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506 (CAS 134556-79-9)
- N-(1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-2-(thiophen-3-yl)acetamide (CAS 1797552-07-8)
- Ethyl 2-bromo-4-cyano-6-(difluoromethyl)benzoate (CAS 1805018-89-6)
- Indeno[1,2,3-kl]acridine (CAS 386-77-6)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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