4-(Chloromethyl)-N-phenyl-1,3-thiazol-2-amine hydrochloride CAS 41981-20-8
| CAS No. | 41981-20-8 |
| Molecular Formula | C10H9ClN2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Chloromethyl)-N-phenyl-1,3-thiazol-2-amine hydrochloride (C10H9ClN2SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-(Chloromethyl)-N-phenyl-1,3-thiazol-2-amine hydrochloride (CAS 41981-20-8) is a high-purity analytical reference standard with the molecular formula C10H9ClN2SHCl and a molecular weight of 261.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Chloromethyl)-N-phenyl-1,3-thiazol-2-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2S HCl |
| Molecular Weight | 261.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
- 7-(Chloromethyl)-2,3-dimethyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-82-5)
- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
- 5-(chloromethyl)-N-(4-methylbenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-24-0)
- 5-(Chloromethyl)-7-ethoxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1000932-47-7)
- 5-(chloromethyl)-N-(4-fluorobenzyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1000932-60-4)
- 2-(Chloromethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine (CAS 1000933-67-4)
Recommended Standards
- 2-Propenal, polymer with 1,2-ethanediamine (CAS 25212-28-6)
- Benzyl 2-methylazepane-1-carboxylate (CAS 1857523-19-3)
- Pteridin-7(8H)-one (CAS 2432-27-1)
- (4-((Tetrahydro-2H-pyran-4-yl)oxy)phenyl)methanamine (CAS 864266-61-5)
- CAS 25281-63-4 (CAS 25281-63-4)
- 4-(2,2,2-Trifluoroethyl)-1H-pyrazole (CAS 1211529-61-1)
- 4-(3-Bromo-5-chloropyridin-2-yl)morpholine (CAS 1199773-36-8)
- (3-phenylpropyl)hydrazine hydrochloride (CAS 24214-86-6)
- 3,3-Difluoro-1-oxa-7-azaspiro[4.5]decane (CAS 1214875-13-4)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com