5-Amino-2-chloro-6-methoxyquinoline CAS 42065-05-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-chloro-6-methoxyquinoline.

CATO supplies 5-Amino-2-chloro-6-methoxyquinoline (CAS 42065-05-4), a certified reference material (molecular formula C10H9ClN2O, MW 208.64 g/mol) for analytical method development and quality control.

The molecular framework of 5-Amino-2-chloro-6-methoxyquinoline (C10H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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