8-Chloro-5-methoxy-2-methylquinoline CAS 420786-79-4
| CAS No. | 420786-79-4 |
| Molecular Formula | C11H10ClNO |
| Molecular Weight | 207.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
8-Chloro-5-methoxy-2-methylquinoline (CAS 420786-79-4), molecular formula C11H10ClNO and molecular weight 207.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Chloro-5-methoxy-2-methylquinoline (C11H10ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO |
| Molecular Weight | 207.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 8-Chloro-4-hydrazinyl-2-methylquinoline (CAS 203626-36-2)
- Hydroxychloroquine Impurity N54 (CAS 5448-52-2)
- 8-Chloro-4-ethoxyquinoline (CAS 64965-29-3)
- N-((1H-imidazol-5-yl)methyl)-3-chloroaniline (CAS 87471-78-1)
- BAY 73-6691 (CAS 794568-92-6)
- 2-(Aminomethyl)-5-chloro-3-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805177-86-9)
- 2-(2,4-Dimethylphenoxy)-N-methylethan-1-amine (CAS 91339-51-4)
- 3-ethyl-2-[(3-ethyl-6-sulfo-1,3-benzothiazol-2-ylidene)hydrazono]-1,3-benzothiazole-6-sulfonic acid (CAS 28752-68-3)
- 2-Chloro-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide (CAS 15777-46-5)
- 3-Formyl-1H-indole-6-carboxylic acid (CAS 887576-06-9)
- (1S)-1-(Naphthalen-2-yl)ethan-1-amine hydrochloride (CAS 1630984-19-8)
- n-Butyl-N-ethylsulfamoyl chloride (CAS 926184-77-2)
- (1S)-1-(oxetan-3-yl)ethanol (CAS 2375165-26-5)
- C-telopeptide (CAS 162929-64-8)
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