2-Methyl-2H-tetrazole-5-thiol CAS 42150-25-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methyl-2H-tetrazole-5-thiol.

2-Methyl-2H-tetrazole-5-thiol (CAS 42150-25-4) is a high-purity analytical reference standard with the molecular formula C2H4N4S and a molecular weight of 116.14 g/mol.

The molecular framework of 2-Methyl-2H-tetrazole-5-thiol (C2H4N4S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Methyl-2H-tetrazole-5-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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