3-Amino-4-(thiophen-2-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide CAS 421584-77-2
| CAS No. | 421584-77-2 |
| Molecular Formula | C13H8F3N3OS2 |
| Molecular Weight | 343.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Amino-4-(thiophen-2-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 421584-77-2) is a high-purity analytical reference standard with the molecular formula C13H8F3N3OS2 and a molecular weight of 343.35 g/mol.
Structurally, 3-Amino-4-(thiophen-2-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (C13H8F3N3OS2) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 343.35 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 3-Amino-4-(thiophen-2-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8F3N3OS2 |
| Molecular Weight | 343.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Amino Standards
- 2-Amino-7-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6-(methylthio)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 127945-63-5)
- 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-((methylthio)methoxy)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 90813-68-6)
- (S)-4-Amino-2-((S)-1-((S)-2,4-diamino-4-oxobutanoyl)pyrrolidine-2-carboxamido)-4-oxobutanoic acid (CAS 194041-51-5)
- Ethyl 2-amino-4-(4-methoxyphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 333340-98-0)
- 5-Amino-N-(2,5-difluorophenyl)-1-(3,4-dimethylphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 1260918-71-5)
- Ethyl 2-amino-6-(hydroxymethyl)-8-oxo-4-phenyl-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate (CAS 194282-60-5)
- 5-Amino-1-(3-fluorobenzyl)-N-(4-fluorobenzyl)-1H-1,2,3-triazole-4-carboxamide (CAS 902557-10-2)
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Recommended Standards
- 3-{3-[(difluoromethyl)sulfanyl]-5-(4-ethoxyphenyl)-4h-1,2,4-triazol-4-yl}propanoic acid (CAS 863667-94-1)
- 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-fluorobutanoic acid (CAS 2260936-15-8)
- 3-(Thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carbohydrazide (CAS 477854-04-9)
- 4-Fluoro-N-(2-phenylquinazolin-4-yl)benzamide (CAS 866155-25-1)
- (3R)-Pyrrolidine-3-thiol hydrochloride (CAS 101394-44-9)
- 2-Cyano-3-(2-thiomethylphenyl)propiophenone (CAS 898754-31-9)
- 2-(Pyrrolidin-2-yl)cyclopentan-1-one (CAS 1423117-68-3)
- 1,4-Dioxaspiro[4.5]decan-6-one (CAS 4746-96-7)
- n-(5-Bromo-2-fluorobenzyl)butan-2-amine (CAS 1019599-47-3)
- 3-(Pyrrolidin-1-yl)quinoxalin-2-amine (CAS 480439-27-8)
- 4,6-Dibromopicolinic acid (CAS 1060815-78-2)
- (R)-Methyl 2-amino-3-(2-methoxyphenyl)propanoate hydrochloride (CAS 915713-04-1)
- Ethyl 4-(6-methylnaphthalen-2-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 219815-16-4)
- Lixisenatide (CAS 320367-13-3)
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