5-Chloro-4-methylthiazol-2-amine hydrochloride CAS 42212-83-9
| CAS No. | 42212-83-9 |
| Molecular Formula | C4H5ClN2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Chloro-4-methylthiazol-2-amine hydrochloride (CAS 42212-83-9) is a high-purity analytical reference standard with the molecular formula C4H5ClN2SHCl and a molecular weight of 185.07 g/mol.
The molecular framework of 5-Chloro-4-methylthiazol-2-amine hydrochloride (C4H5ClN2SHCl) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H5ClN2S HCl |
| Molecular Weight | 185.07 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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- Polyphenylenesulfide (CAS 26125-40-6)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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